1、How is uric acid produced?
Uric acid is the end product of purine metabolism in the body, the synthesis of uric acid is by the body of amino acids, carbon dioxide, ribose phosphate, and adenosine triphosphate (ATP) together, and after the role of certain enzymes in the body to form adenine, and then in the body of xanthine oxidase or hypoxanthine converting enzyme in the role of generating uric acid.
2、Which people need to be alert to high uric acid?
Lack of exercise, drinking and smoking, irregular life, mental stress, staying up late, high purine diet, high blood pressure, high blood lipids, cardiovascular disease, diabetes, kidney disease, female menopause, etc. and suffer from hyperuricemia have a great relationship. FITAOS Max 2 smartwatch is very suitable for this kind of people, the blood pressure, blood lipids, blood glucose, and blood oxygen of the specific data can be displayed in the APP, when these data appear abnormal, then you need to watch out for these people. When these data appear abnormal, you should be alert to high uric acid.
3、What diseases can high uric acid cause?
Elevated levels of uric acid in the blood may be deposited in many tissues and organs, causing diseases:
(1) Kidney diseases
Increased blood uric acid will allow more uric acid crystals to be deposited, directly causing renal vascular damage and chronic renal interstitial disease, resulting in acute and chronic uric acid nephropathy, urinary tract stones, renal insufficiency, and other diseases; conversely, renal insufficiency is also an important risk factor for hyperuricemia.
(2) Hypertension, cardiovascular and cerebrovascular diseases
Research shows that long-term accumulation of uric acid precipitation in the blood vessel wall, can damage the arterial endothelium, cause vascular endothelial cell dysfunction, the formation of thrombus, promote the process of atherosclerosis and platelet aggregation, and accelerate the deposition of lipids in the blood vessel wall. Patients with hypertension complications caused by high uric acid can use the FITAOS Max 2 smartwatch to monitor both uric acid and blood lipids in their bodies and can show the data to their doctors when they visit the doctor to assist with related treatments.
For every 60 μmol/L increase in blood uric acid level, the relative risk of developing hypertension increases by 13%, and the risk of death from coronary heart disease increases by 12%. Patients with hyperuricemia have a 47% increased risk of stroke and a 26% increased risk of stroke death.
(3) Gouty arthritis, gout stones
A large number of urate crystals deposited in the joint cavity can induce gouty arthritis. It manifests as sudden joint pain late at night, which is tear-like or knife-like pain, accompanied by redness and swelling of the joints, and elevated local skin temperature, which affects walking in severe cases.
If uric acid is not well treated, resulting in recurrent attacks of gout, a large number of urate crystals will be deposited in the subcutaneous, joint cavity, and clumped together to form gout stone, resulting in joint bone damage, and deformity.
(4) Diabetes
Studies have shown that for every 60μmol/L increase in blood uric acid levels, the risk of new-onset diabetes mellitus increases by 17%, and 20% to 50% of patients with hyperuricemia suffer from diabetes mellitus. Conversely, having diabetes for a long time will also affect the metabolism of purines.
(5) Obesity and hyperlipidemia
Studies show that the proportion of hyperuricemia people combined with hyperlipidemia and obesity is as high as 68% and 71% in women and men, respectively. Obese people do not pay attention to diet control, it is easy to have high uric acid. A portion of patients have improved their weight after regular and effective uric acid-lowering treatment. Similarly, standardized lipid-lowering treatment is also conducive to the reduction of blood uric acid. FITAOS Max 2 smartwatch can measure the composition of blood lipids, assisting patients to monitor the level of blood lipids, to avoid the hidden danger of high uric acid.
4、How to ensure that the uric acid maintains a normal value?
(1) Establish a reasonable and nutritionally balanced diet plan
Adopt a healthy lifestyle, avoid high purine food (seafood, animal offal, thick gravy soup, etc.) large intake, daily purine intake of <150mg.
Preferred protein sources are foods with low purine content, such as milk, eggs, etc.; abstain from drinking alcohol (alcohol metabolism can increase the concentration of lactic acid in the blood, which can inhibit the secretion of uric acid by the renal tubules and reduce the ability of the kidney to excrete uric acid).
Eating fewer sweets and fructose-containing beverages, drinking more water (more than 2,000 ml), and alkalizing urine (you can use pH test paper to measure if it is at 6~6.5, then alkalization has been achieved) can promote uric acid excretion.
In addition, different food preparation and cooking methods (boiling or blanching, which can reduce the purine value of food) can also affect the purine level in food.
(2) Exercise moderately and control weight
Exercise more (but avoid strenuous exercise), subject to slight sweating, and choose suitable exercise methods, such as swimming, simple yoga, cycling, etc., to promote the metabolic rate and improve mental pleasure.FITAOS Max 2 smartwatch has an embedded artificial intelligence model that can conduct professional exercise analysis, and formulate a personalized exercise plan for patients with high uric acid to assist in the decline of uric acid.
(3) Adhere to scientific medication
Reducing uric acid requires long-term, systematic treatment, and is a gradual process, in the doctor's standardized guidance, tailor-made “individualized” uric acid reduction program. Be careful to use drugs that may affect the excretion of uric acid or drugs that can make uric acid decline.
(4) Emphasize daily data
Daily uric acid data is more important for asymptomatic hyperuricemia patients, The FITAOS Max 2 smartwatch can give uric acid analysis reports according to each person's situation, which can let patients always know their situation. If there are abnormal fluctuations in the data, it is necessary to go to the hospital to do ordinary routine blood sampling to reflect whether the blood uric acid value exceeds the standard, early detection, and early treatment, to prevent the problem before it occurs.